INFLAMMATORY ACTIVITY AND RENAL PATHOLOGY IN LUPUS NEPHRITIS

Authors

  • Hamraeva Nasiba Abdurasulovna Assistant, PhD Department: Internal medicine, nephrology and hemodialysis Tashkent Pediatric Medical Institute,
  • Islamova Kamola Akramovna Assistant, PhD Department of Internal Medicine No. 1, Samarkad State Medical Institute, Samarkand, Uzbekistan
  • Abdushukurova Komila Rustamovna Senior Lecturer, Department of Internal Medicine No. 1, Samarkad State Medical Institute, Samarkand, Uzbekistan
  • Xamrayev Botir Egamkulovich Magistr, Department of Internal Medicine No. 1, Samarkad State Medical Institute, Samarkand, Uzbekistan.

Keywords:

systemic lupus erythematosus, kidney disease, tumor necrosis factor α, C-reactive protein.

Abstract

To solve the problems in the surveyed 45 patients: examination, laboratory complex, immune and instrumental methods. All 45 patients with SLE kidney disease manifested itself in the form of lupus nephritis. Syndrome hypertension vstre-chalsya in 35.5% of cases, the syndrome of chronic renal failure in 37.7% of cases. Urinary syndrome characterized by moderate proteinuria (75.5%), hematuria (73.3%) and leukocyturia (73.3%). Positive correlation of tumor necrosis factor α, C-reactive protein level of creatinine, urea, ESR and SLE activity, which confirms the participation of the factors described in the immune process lupus inflammation.

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Published

2023-03-27

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Section

Articles

How to Cite

INFLAMMATORY ACTIVITY AND RENAL PATHOLOGY IN LUPUS NEPHRITIS. (2023). Spectrum Journal of Innovation, Reforms and Development, 13, 89-94. https://sjird.journalspark.org/index.php/sjird/article/view/583

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